Developmental approaches to create new organs

Producing new organs from human stem cells would be enormously useful for research and therapeutic purposes. A subset of current methods aims to build organs, either by seeding acelullar scaffolds with progenitor cells, or by making use of 3D culture systems. Additionally, newly established technologies aim to generate whole human organs within host animal “containers” in vivo. In this lecture, Dr Christodoulos Xinaris will analyse these strategies, with special emphasis on the regeneration of the kidney, and discuss how these technologies could be employed to generate patient-specific organs from in vitro expanded cells, an ability that could potentially solve the problem of finding compatible donor organs

CELL MODEL SYSTEMS SUMMER SCHOOL